Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.631


Transcription factors associated with POU5F1_SOX2{dimer}.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX2hg19_v1_chr3_+_181429711_1814297150.431.4e-02Click!
POU5F1hg19_v1_chr6_-_31134614_311346140.154.0e-01Click!


Activity profile for motif POU5F1_SOX2{dimer}.p2.

activity profile for motif POU5F1_SOX2{dimer}.p2


Sorted Z-values histogram for motif POU5F1_SOX2{dimer}.p2

Sorted Z-values for motif POU5F1_SOX2{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1_SOX2{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_216241321 12.718 FN1
fibronectin 1
chr3_+_133494275 5.563 TF
transferrin
chr4_+_100495972 4.978 MTTP
microsomal triglyceride transfer protein
chr10_+_7745325 4.528 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr8_+_120079423 4.348 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr11_+_69455938 4.342 CCND1
cyclin D1
chr8_-_17752847 4.306 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr12_-_91573264 4.298 NM_133503
DCN
decorin
chr17_+_27370155 4.291 PIPOX
pipecolic acid oxidase
chr16_-_55867016 4.287 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr11_-_35441501 4.283 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr9_+_6215785 4.178 NM_001199640
NM_001199641
NM_033439
IL33


interleukin 33


chr10_+_7745229 4.064 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745284 3.959 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_49229994 3.918 NM_001014986
NM_001193471
NM_001193472
NM_001193473
NM_004476
FOLH1




folate hydrolase (prostate-specific membrane antigen) 1




chr11_+_69455884 3.914 CCND1
cyclin D1
chr17_+_27369917 3.813 NM_016518
PIPOX
pipecolic acid oxidase
chr4_+_77610610 3.766 SHROOM3
shroom family member 3
chr5_-_39364562 3.740 NM_001737
C9
complement component 9
chr11_+_69455837 3.728 NM_053056
CCND1
cyclin D1
chr16_+_72088507 3.701 NM_001126102
NM_005143
HP

haptoglobin

chr3_-_42917191 3.692 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr8_-_26724728 3.607


chr12_+_20963637 3.584 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr13_-_86373328 3.543 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr2_-_216289936 3.480 FN1
fibronectin 1
chr10_+_7745354 3.432 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr17_-_67138013 3.354 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr2_+_169659099 3.338 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr10_+_96522457 3.332 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr17_-_64225496 3.293 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr19_+_7828034 3.282 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr17_+_3379295 3.262 NM_000049
ASPA
aspartoacylase
chr4_-_187644983 3.242 NM_005245
FAT1
FAT tumor suppressor homolog 1 (Drosophila)
chr9_-_104145800 3.214 NM_001127610
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr3_+_153838791 3.189 NM_001251962
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr7_+_136553398 3.119 NM_001006627
NM_001006630
CHRM2

cholinergic receptor, muscarinic 2

chr11_+_69455978 3.023 CCND1
cyclin D1
chr2_-_175712276 2.833 NM_001206602
CHN1
chimerin (chimaerin) 1
chr16_-_21314371 2.829 NM_001014444
NM_001888
CRYM

crystallin, mu

chr8_-_26724748 2.735 ADRA1A
adrenergic, alpha-1A-, receptor
chr17_+_12623605 2.670 NM_001146313
MYOCD
myocardin
chr1_-_120311466 2.609 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr2_+_74120132 2.434 ACTG2
actin, gamma 2, smooth muscle, enteric
chr8_-_86253863 2.385 NM_001164830
CA1
carbonic anhydrase I
chr4_+_187187342 2.370 F11
coagulation factor XI
chr5_-_176836488 2.364 F12
coagulation factor XII (Hageman factor)
chr6_-_43276529 2.356 NM_206922
CRIP3
cysteine-rich protein 3
chr4_+_77610719 2.343 SHROOM3
shroom family member 3
chr2_+_74120092 2.333 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr1_+_57320442 2.275 NM_000562
C8A
complement component 8, alpha polypeptide
chr19_-_48389514 2.251 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr7_-_16505292 2.250 NM_015464
SOSTDC1
sclerostin domain containing 1
chr3_-_9920633 2.229 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr10_-_52645430 2.194 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr1_+_50574589 2.168 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr6_-_138820580 2.151


chr9_-_13250313 2.142 NM_003829
MPDZ
multiple PDZ domain protein
chr3_-_165555167 2.125 BCHE
butyrylcholinesterase
chr15_+_65337707 2.113 NM_178859
OSTBETA
organic solute transporter beta
chr10_-_96829074 2.109 NM_000770
NM_001198853
NM_001198854
NM_001198855
CYP2C8



cytochrome P450, family 2, subfamily C, polypeptide 8



chr4_+_77356252 2.098 NM_020859
SHROOM3
shroom family member 3
chr7_-_16844606 2.096 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chr2_+_234600320 2.075 NM_205862
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr2_+_233734993 2.070 NM_206895
C2orf82
chromosome 2 open reading frame 82
chr13_-_28543290 2.006 NM_001265
CDX2
caudal type homeobox 2
chr12_-_14996381 1.993 NM_021071
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr4_+_184826427 1.979 NM_020225
STOX2
storkhead box 2
chr8_-_27115897 1.956 NM_030795
STMN4
stathmin-like 4
chr7_-_107443631 1.905 NM_000111
SLC26A3
solute carrier family 26, member 3
chr5_+_118965253 1.900 NM_001163991
NM_182761
FAM170A

family with sequence similarity 170, member A

chr2_-_231989755 1.893 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr10_+_5005685 1.835 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr7_+_89843133 1.830 NM_001040666
STEAP2
STEAP family member 2, metalloreductase
chr3_-_42305438 1.828 NM_001174138
CCK
cholecystokinin
chr4_-_110723334 1.826 NM_000204
CFI
complement factor I
chr1_+_163038934 1.825 NM_001113381
RGS4
regulator of G-protein signaling 4
chr9_-_140196702 1.818 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr5_+_173472692 1.798 NM_015980
HMP19
HMP19 protein
chr6_-_138820578 1.791 NM_001144060
NHSL1
NHS-like 1
chr17_+_32582295 1.778 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr5_-_135290521 1.775 NM_002302
LECT2
leukocyte cell-derived chemotaxin 2
chr12_-_21487831 1.764 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr2_+_211458078 1.752 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr1_+_50574601 1.738 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_-_177133950 1.738 NM_004319
NM_207108
ASTN1

astrotactin 1

chr11_+_112047088 1.725 NM_001037290
BCO2
beta-carotene oxygenase 2
chr8_+_76452202 1.718 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr14_+_39703119 1.716 NM_054024
MIA2
melanoma inhibitory activity 2
chr5_-_176836535 1.698 NM_000505
F12
coagulation factor XII (Hageman factor)
chr10_+_5005601 1.689 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr2_-_21225640 1.659 APOB
apolipoprotein B (including Ag(x) antigen)
chr11_+_112046207 1.658 NM_031938
BCO2
beta-carotene oxygenase 2
chr3_-_148939784 1.649 NM_000096
CP
ceruloplasmin (ferroxidase)
chr22_+_18043147 1.614 NM_031481
SLC25A18
solute carrier family 25 (mitochondrial carrier), member 18
chr1_+_196946666 1.609 NM_030787
CFHR5
complement factor H-related 5
chr1_+_101185195 1.600 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr11_-_118047336 1.599 NM_004588
SCN2B
sodium channel, voltage-gated, type II, beta
chr18_+_29171729 1.593 NM_000371
TTR
transthyretin
chr4_-_70361578 1.592 NM_021139
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr4_+_74281884 1.585 ALB
albumin
chr13_-_28543143 1.559 CDX2
caudal type homeobox 2
chr14_-_106641585 1.541 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr10_+_5005453 1.532 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr1_+_87012758 1.514 NM_012128
CLCA4
chloride channel accessory 4
chr3_+_63428752 1.512 NM_144642
SYNPR
synaptoporin
chr4_+_187187117 1.487 NM_000128
F11
coagulation factor XI
chr4_-_41750936 1.477 NM_003924
PHOX2B
paired-like homeobox 2b
chr17_+_3377346 1.477 NM_001128085
ASPA
aspartoacylase
chr2_-_50574891 1.467 NM_138735
NRXN1
neurexin 1
chr7_+_29519485 1.464 NM_001039936
CHN2
chimerin (chimaerin) 2
chr20_-_9819406 1.430 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr13_+_97794050 1.422 MBNL2
muscleblind-like 2 (Drosophila)
chr10_-_5045967 1.418 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr7_+_1126442 1.402 NM_001039966
NM_001505
GPER

G protein-coupled estrogen receptor 1

chr3_-_165555252 1.395 NM_000055
BCHE
butyrylcholinesterase
chr8_-_27115935 1.391 STMN4
stathmin-like 4
chr1_-_112106562 1.389 NM_001081976
ADORA3
adenosine A3 receptor
chrX_+_138612894 1.380 NM_000133
F9
coagulation factor IX
chr19_-_5838740 1.377 FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr10_-_69597768 1.366 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr3_-_93747453 1.361 NM_001001850
STX19
syntaxin 19
chr5_+_176516550 1.350 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr18_-_61329113 1.340 NM_006919
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chrX_-_15402469 1.327 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr12_+_21284127 1.308 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr1_+_81771844 1.302 LPHN2
latrophilin 2
chr9_+_97488993 1.299 C9orf3
chromosome 9 open reading frame 3
chr3_-_52864687 1.293 NM_001166449
NM_002218
ITIH4

inter-alpha-trypsin inhibitor heavy chain family, member 4

chr13_-_28543423 1.273 CDX2
caudal type homeobox 2
chr18_-_3845295 1.273 NM_001003809
NM_001242765
NM_001242766
DLGAP1


discs, large (Drosophila) homolog-associated protein 1


chr16_+_76311175 1.252 NM_033401
CNTNAP4
contactin associated protein-like 4
chr1_+_196912910 1.233 NM_005666
CFHR2
complement factor H-related 2
chr3_-_170744767 1.231 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chrX_+_144908927 1.229 NM_004709
CXorf1
chromosome X open reading frame 1
chr13_-_110802708 1.201 COL4A1
collagen, type IV, alpha 1
chr4_-_155511838 1.177 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr3_+_2933898 1.172 NM_001206956
NM_175613
CNTN4

contactin 4

chr9_-_74675498 1.170 NM_001128618
C9orf57
chromosome 9 open reading frame 57
chr4_-_176733413 1.158 GPM6A
glycoprotein M6A
chr6_+_131894343 1.157 NM_000045
NM_001244438
ARG1

arginase, liver

chr2_+_182850550 1.156 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr5_+_173472737 1.153 HMP19
HMP19 protein
chr3_+_100238063 1.153 TMEM45A
transmembrane protein 45A
chr7_-_8302141 1.152 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chr14_-_107170400 1.141 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr6_+_153071931 1.139 NM_003381
NM_194435
VIP

vasoactive intestinal peptide

chr2_-_224467142 1.137 NM_003469
SCG2
secretogranin II
chr12_-_102874373 1.125 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr17_-_42908178 1.118 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr11_+_63057371 1.109 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr3_+_89156673 1.108 NM_005233
NM_182644
EPHA3

EPH receptor A3

chr12_-_102874340 1.106 IGF1
insulin-like growth factor 1 (somatomedin C)
chr12_+_41831484 1.105 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr5_+_140771482 1.103 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chr11_-_18258315 1.088 SAA4
serum amyloid A4, constitutive
chr14_-_106733392 1.074 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_-_216242916 1.067 FN1
fibronectin 1
chr8_-_120651019 1.063 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr19_-_51961648 1.051 NM_014442
SIGLEC8
sialic acid binding Ig-like lectin 8
chr4_-_41750722 1.051 PHOX2B
paired-like homeobox 2b
chr2_+_113885145 1.050 IL1RN
interleukin 1 receptor antagonist
chr3_+_108021331 1.046 NM_007072
HHLA2
HERV-H LTR-associating 2
chr2_+_166326156 1.044 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr4_-_176733378 1.041 GPM6A
glycoprotein M6A
chrX_-_139047676 1.038 NM_001013403
CXorf66
chromosome X open reading frame 66
chr1_+_16083132 1.036 FBLIM1
filamin binding LIM protein 1
chr19_-_5839702 1.034 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr14_-_106452693 1.021 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_+_162602198 1.016 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr2_+_234826042 1.013 NM_024080
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr3_+_2280512 1.013 NM_001206955
CNTN4
contactin 4
chr12_-_102874158 1.013 IGF1
insulin-like growth factor 1 (somatomedin C)
chr12_-_27599557 0.992 ARNTL2
aryl hydrocarbon receptor nuclear translocator-like 2
chr7_-_122339186 0.985 NM_139175
RNF133
ring finger protein 133
chr4_-_122085475 0.980 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr5_+_125758818 0.971 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr2_+_135596185 0.967 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr10_+_7745341 0.963 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chrX_+_142113703 0.958 NM_001009613
SPANXN4
SPANX family, member N4
chr18_-_28622624 0.957 NM_001941
NM_024423
DSC3

desmocollin 3

chr19_+_56270506 0.949 NM_001145014
RFPL4A
ret finger protein-like 4A
chr5_+_161277702 0.947 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_-_186578122 0.946 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr19_+_42259397 0.935 NM_002483
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr18_-_58040000 0.924 NM_005912
MC4R
melanocortin 4 receptor
chr15_+_22736245 0.915 NM_001001413
GOLGA6L1
golgin A6 family-like 1
chr6_-_49754899 0.901 NM_138733
PGK2
phosphoglycerate kinase 2
chr18_+_46065367 0.886 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr2_+_90077732 0.881


chr3_-_149095413 0.870 TM4SF1
transmembrane 4 L six family member 1
chr10_+_114133775 0.867 ACSL5
acyl-CoA synthetase long-chain family member 5
chr3_+_159557649 0.866 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr12_-_8815370 0.862 NM_003480
MFAP5
microfibrillar associated protein 5
chr9_+_97521930 0.862 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr11_+_60524339 0.861 NM_001098835
NM_152717
MS4A15

membrane-spanning 4-domains, subfamily A, member 15

chr4_-_6422844 0.859 NM_001206996
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr12_+_18891040 0.854 NM_033328
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr9_+_131684561 0.849 NM_001100877
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr9_+_74729510 0.824 NM_001242507
GDA
guanine deaminase

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
27.05 3.14e-07 GO:0008206 bile acid metabolic process
46.92 1.28e-06 GO:0015721 bile acid and bile salt transport
7.43 1.62e-05 GO:0008202 steroid metabolic process
16.41 2.04e-05 GO:0072376 protein activation cascade
5.96 7.25e-05 GO:0032787 monocarboxylic acid metabolic process
3.71 6.13e-04 GO:0006082 organic acid metabolic process
3.20 9.05e-04 GO:0006629 lipid metabolic process
41.70 1.35e-03 GO:0043252 sodium-independent organic anion transport
3.23 1.40e-03 GO:0009611 response to wounding
3.60 1.88e-03 GO:0019752 carboxylic acid metabolic process
3.60 1.88e-03 GO:0043436 oxoacid metabolic process
3.52 2.56e-03 GO:0042180 cellular ketone metabolic process
13.91 3.22e-03 GO:0002526 acute inflammatory response
29.44 6.28e-03 GO:0007597 blood coagulation, intrinsic pathway
12.11 7.27e-03 GO:0015718 monocarboxylic acid transport
1.55 7.72e-03 GO:0050896 response to stimulus
3.64 1.19e-02 GO:0050878 regulation of body fluid levels
25.03 1.26e-02 GO:0072378 blood coagulation, fibrin clot formation
10.01 2.19e-02 GO:0002576 platelet degranulation
41.70 2.97e-02 GO:0031638 zymogen activation
2.08 3.15e-02 GO:0065008 regulation of biological quality
9.39 3.16e-02 GO:0006959 humoral immune response
6.26 3.19e-02 GO:0046942 carboxylic acid transport
6.18 3.48e-02 GO:0015849 organic acid transport
125.10 4.65e-02 GO:0001897 cytolysis by symbiont of host cells
125.10 4.65e-02 GO:0001907 killing by symbiont of host cells
125.10 4.65e-02 GO:0019836 hemolysis by symbiont of host erythrocytes
125.10 4.65e-02 GO:0044004 disruption by symbiont of host cells
125.10 4.65e-02 GO:0044179 hemolysis in other organism
125.10 4.65e-02 GO:0051715 cytolysis in other organism
125.10 4.65e-02 GO:0051801 cytolysis in other organism involved in symbiotic interaction
125.10 4.65e-02 GO:0052025 modification by symbiont of host cell membrane
125.10 4.65e-02 GO:0052043 modification by symbiont of host cellular component
125.10 4.65e-02 GO:0052111 modification by symbiont of host structure
125.10 4.65e-02 GO:0052185 modification of structure of other organism involved in symbiotic interaction
125.10 4.65e-02 GO:0052188 modification of cellular component in other organism involved in symbiotic interaction
125.10 4.65e-02 GO:0052331 hemolysis in other organism involved in symbiotic interaction
125.10 4.65e-02 GO:0052332 modification by organism of cell membrane in other organism involved in symbiotic interaction

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.02 2.49e-10 GO:0005576 extracellular region
4.37 2.47e-08 GO:0005615 extracellular space
3.50 1.38e-06 GO:0044421 extracellular region part
3.28 3.96e-04 GO:0005624 membrane fraction
14.44 4.90e-04 GO:0031983 vesicle lumen
3.17 6.42e-04 GO:0005626 insoluble fraction
53.62 2.39e-03 GO:0005577 fibrinogen complex
13.31 4.96e-03 GO:0031093 platelet alpha granule lumen
13.04 5.50e-03 GO:0034774 secretory granule lumen
12.52 6.72e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
10.98 1.27e-02 GO:0031091 platelet alpha granule
2.42 2.98e-02 GO:0000267 cell fraction
1.91 3.87e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
18.77 1.26e-04 GO:0003823 antigen binding
93.82 3.49e-04 GO:0047023 androsterone dehydrogenase activity
93.82 3.49e-04 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
125.10 1.12e-02 GO:0047026 androsterone dehydrogenase (A-specific) activity
125.10 1.12e-02 GO:0047718 indanol dehydrogenase activity
3.78 2.97e-02 GO:0030246 carbohydrate binding
25.03 3.72e-02 GO:0008514 organic anion transmembrane transporter activity
23.46 4.56e-02 GO:0015125 bile acid transmembrane transporter activity